Galagwe Moyana and Joel Mogorosi were both on the scoresheet as Botswana brushed aside Eritrea 2-0 on Saturday afternoon.
The 2018 FIFA World Cup qualification (CAF) first round first-leg clash was played at the Cicero Stadium in Asmara.
The home side were the first to threaten six minutes into the game through Henok Goitom, but his effort could not trouble Botswana goalkeeper Kabelo Dambe.
Ten minutes later, the Zebras launched an attack through Kabelo Seakanyeng, who then forced Eritrea goalkeeper Haylegiorgis Gebregziabiher into a decent save.
Botswana were doing most of the attacking, and they were rewarded for their efforts in the 21st minute when Township Rollers midfielder Galagwe Moyana made 1-0 to the visitors.
The Red Sea Boys looked vulnerable to conceding each time they lost the ball in the Zebras half, and the latter launched quick counter-attacks.
Nevertheless, Eritrea were able to contain the visitors until Egyptian referee Ibrahim Nour El Din blew the whistle for half-time.
The Zebras continued to dominate in the second-half, and another Rollers player Joel Mogorosi doubled Botswana's lead with a low strike four minutes after the hour-mark.
In the dying minutes of the game, Botswana coach Peter Butler introduced Lemponye Tshireletso, and Segolame Boy for Mogakolodi Ngele and Kabelo Seakanyeng respectively.
Ultimately, the match ended 2-0 on the day in favour of Botswana. Eritrea face a mammoth task to overturn the deficit in the second-leg which will be played in Francistown on Tuesday.
Eritrea XI: Gebregziabiher, Gebregzgabhier, Golon, Andebahan, Birhane, Muruts, Selomon, Alexander, Abreha, Negassie, Goitom.
Botswana XI: Dambe, Gaolaolwe, Sosome, Mafoko, Nato, Ditsile, Seakanyeng, Moyana, Mogorosi, Ngele, Moyo.