Ivory Coast overcame Liberia 1-0 thanks to a lone goal from Gohi Cyriac in the first-half on Friday night.
The 2018 FIFA World Cup qualification (CAF) second-round first leg clash was played at the Antoinette Tubman Stadium in Monrovia.
The Elephants managed to beat the Lone Stars without three key players Wilfried Boy, Solomon Kalou and Yaya Toure.
The Lone Stars were able to contain Ivory Coast in the opening stages of the first-half as the away side looked to grab an early goal.
However, Gohi Cyriac broke the deadlock on the stroke of half-time to hand the Elephants the lead heading into the break.
There were no goals in the second-half as the two teams failed to beat the two goalkeepers Songo and Sylvain Gbohouo.
Ultimately, Tunisian referee Youssef Essrayri blew the final whistle and Ivory Coast walked away 1-0 winners on the night.
The second-leg is scheduled to take place at the Stade Félix Houphouët-Boigny in Abidjan on Tuesday. Congolese referee Lazard Tsiba will be in charge.
Ivory Coast 1 (Cyriac 44')
Liberia XI: Songo, Dennis Jr, Wleh (Williams 21'), Glay, Gerhardt (Keita 46'), Grimes, Jebor, Krangar, Johnson (Tisdell 63'), Laffor, Marshall.
Ivory Coast XI: Gbohouo, Viera, Akpro (Diomande 52'), Boka, Seri, Aurier, Die, Kone, Gervinho, Cyriac (Sio 65'), Doumbia (Bakayoko 95').